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Rudolph's PediatricsRudolph's Pediatrics

Section 18. Disorders of the Skin > 

Chapter 358. Disorders of the Epidermis

Kristen E. Holland
Topics Discussed: dermatitis; dermatology; eczema; pediatric dermatology; skin disorder.
Sections: Atopic Dermatitis, Contact Dermatitis, Other Eczematous Dermatitides, Seborrheic Dermatitis, Diaper Dermatitis, Dermatitis Secondary to Nutritional and Metabolic Disorders, Psoriasis, Other Papulosquamous Disorders, Aquatic Dermatitis, References.
Excerpt:"Primary skin diseases that principally affect the epidermis may be categorized as either a dermatitis or a papulosquamous disorder. Dermatitis commonly denotes inflammation of the epidermis. Eczema generically denotes edema within the epidermis. Many primary dermatitides are eczematous in nature, although the term eczema is often misused interchangeably for atopic dermatitis. In its mildest or chronic form, edema is seen histopathologically as prominent, toothlike interconnections between keratinocytes (spongiosis). With more intracellular fluid accumulation, intraepidermal vesicles are formed. Vesicles are often subclinical in subacute or chronic eczemas where edema is mild but present as grossly evident vesicles and bullae in acute eczemas. Papulosquamous eruptions are characterized by the presence of erythematous papules or plaques with overlying scale. While eczematous processes clinically manifest with weeping or crusting, papulosquamous disorders are associated with little to no edema and thus clinically tend to be dry...."
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